08
10
2015
Researchers at the University of Texas MD Anderson Cancer Center say they have gained new insights on the role of fumarase in DNA repair. They published their study (“Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation”) in Nature Cell Biology.
08
07
2015
Cesium chloride- and iodixanol-based density gradients represent the core step in most protocols for serotype-independent adeno-associated virus (AAV) purification.
08
07
2015
Ten biopharma companies have joined together to create the Genomics Genomics Expert Network for Enterprises (GENE) Consortium, which will oversee a year-long trial designed to integrate industry expertise into the 100,000 Genomes Project—the U.K.’s effort to catapult itself to global leadership in genetic research into cancer and rare diseases.
08
06
2015
While all cells in the body rely on metabolic pathways that take place within the mitochondria, the cells of some organs, such as the brain and heart, have an essential demand for constant energy. Maintaining the proper mitochondrial homeostasis is critical for overall tissue health, as defective mitochondria have been linked to a number of disease states.
08
06
2015
A microtubule-inspired microfluidic system that resembles a microscopic forest of arms can pluck biomolecules out of liquid mixtures, carry them from one chemical stream to another, and then release them. The system, which is dynamic and tunable, may be suitable for applications in clinical diagnostics, target characterization, environmental analysis, and chemical purification.
