High-Throughput Screening and Compound Screening Service

저자：   업로드：2017-06-05  조회수：

    High-throughput screening (HTS) is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology and chemistry. Using robotics, data processing/control software, liquid handling devices and sensitive detectors, high-throughput screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests. Through this process, one can rapidly identify active compounds, antibodies, or genes that modulate a particular bio molecular pathway. The results of these experiments provide starting points for drug design and for understanding the interaction or role of a particular biochemical process in biology.

    HTS is a relatively recent innovation, made feasible largely through modern advances in robotics and high-speed computer technology. It still takes a highly specialized and expensive screening lab to run an HTS operation, so in many cases a small- to moderate-size research institution will use the services of an existing HTS facility rather than set up one for it.

    Compound screening is a pharmacochemical study. The chemical activity of the compound produced in Medicilon is generally more than 95% in the purity of the initial screening activity. The purity of the compound activity test can reach more than 98% for animal experiments or repeated screening experiments in the later stage.

    Drug screening will be based on self-built or imported drug screening model, the development and improvement of molecular and cellular levels of high-throughput screening model for the screening method, tissue, organ and animal level screening model for re-screening drug screening system. Provide compound biological activity testing services and technology platform for colleges and universities, research institutes and pharmaceutical companies.

    Medicilon has completed dozens of drug research projects for clients and successfully identified several drug candidates for clinical trials. Our team provides the following services:

- Target Assessment - Drug Targets

- HITs Identification

- Lead Optimization

- Clinical Candidate Nomination

- Computer Aided Drug Design

- SAR Study

    With our extensive experience in medicinal chemistry, we are able to promote drug discovery programs into development and clinical trial stage efficiently and cost-effectively.

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