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  • 08
    04

    2015

    Single Nuclear Protein Orchestrates Stem Cell Development

    Think of an especially active, hands-on orchestra conductor who shuns the podium, roams the orchestra pit, and urges principle musicians from diverse ensembles to play together and realize the score. That’s roughly what happens during stem cell development, except the conductor is a single “master” growth factor receptor, the orchestra pit is the nucleus, the principal musicians and instrumental ensembles are promoters and transcription factors, and the score is, well, ontogenesis itself.

  • 08
    04

    2015

    Scientists Use Molecular Can Opener to Target HIV

    One of the main roadblocks that have stymied researchers’ attempts at generating an effective HIV vaccine is somehow managing to get antibodies and other immune cells to attack the appropriate targets that are practically hermetically sealed within the virus.

  • 08
    03

    2015

    Highly Conserved DNA Repair Proteins Have Role in Cancer Predisposition

    During evolution and development of a species, the replication of the organism’s genome can lead to a duplication of certain genes that evolve new functions. These so-called paralogs are found throughout the genome of humans, as well as other organisms, and are associated with a variety of cellular processes.

  • 08
    03

    2015

    Bioinformatics Program Better Matches Cancer Patients with Treatments

    Scientists at the University of Colorado Cancer Center have described a new tool that reportedly improves the ability to match drugs to disease. 

  • 07
    31

    2015

    Tumor Microenvironment Impacts Cancer Subtype Progression

    Scientists at Cold Spring Harbor Laboratory (CSHL) report that two different mouse models of breast cancer progressed differently based on characteristics of the tumor microenvironment, which is the area of tissue in which the tumor is embedded. The team published its study (“Presence of Insulin-Like Growth Factor Binding Proteins Correlates With Tumor-Promoting Effects of Matrix Metalloproteinase 9 in Breast Cancer”) in Neoplasia.