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  • 08
    10

    2015

    Urine Proteins Point to Early-Stage Pancreatic Cancer

    Raising hopes for a simple, noninvasive, inexpensive, and easily repeatable test for pancreatic cancer, scientists at Barts Cancer Institute, Queen Mary University, have developed a three-protein biomarker panel that can screen urine samples to identify pancreatic cancer when it is still in its early stages.

  • 08
    10

    2015

    Researchers Provide Critical New Insights on DNA Repair

    Researchers at the University of Texas MD Anderson Cancer Center say they have gained new insights on the role of fumarase in DNA repair. They published their study (“Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation”) in Nature Cell Biology.

  • 08
    07

    2015

    Purification of Recombinant AAV Vectors for Preclinical Applications

    Cesium chloride- and iodixanol-based density gradients represent the core step in most protocols for serotype-independent adeno-associated virus (AAV) purification.

  • 08
    07

    2015

    Biopharmas Team Up with U.K.'s 100,000 Genomes Project

    Ten biopharma companies have joined together to create the Genomics Genomics Expert Network for Enterprises (GENE) Consortium, which will oversee a year-long trial designed to integrate industry expertise into the 100,000 Genomes Project—the U.K.’s effort to catapult itself to global leadership in genetic research into cancer and rare diseases.

  • 08
    06

    2015

    Link between Mitochondrial Protein and Heart Failure Uncovered

    While all cells in the body rely on metabolic pathways that take place within the mitochondria, the cells of some organs, such as the brain and heart, have an essential demand for constant energy. Maintaining the proper mitochondrial homeostasis is critical for overall tissue health, as defective mitochondria have been linked to a number of disease states.